What is the regulation of oxidative phosphorylation by ADP called? What is the regulation of oxidative phosphorylation by ADP called? Answer: acceptor or respiratory control
What is the rate of oxidative phosphorylation determined by? What is the rate of oxidative phosphorylation determined by? Answer: need for ATP and energetic needs of cell
About how many molecules of ATP does the complete oxidation of glucose generate? About how many molecules of ATP does the complete oxidation of glucose generate? Answer: 30, 26 from oxidative phosphorylation
The entry of ______ into mito is coupled by the exit of _______. The entry of ______ into mito is coupled by the exit of _______. Answer: ADP, ATP (ATP-ADP translocate)
What shuttle is used by the heart and liver? What shuttle is used by the heart and liver? Answer: malate-aspartate
How do electrons from cytoplasmic NADH enter the mitochondria? How do electrons from cytoplasmic NADH enter the mitochondria? Answer: shuttles
What is true about the number of c rings? What is true about the number of c rings? Answer: determines the number of protons required to synthesize a molecule of ATP
What powers ATP synthesis? What powers ATP synthesis? Answer: proton flow around c ring which powers the movement of the gamma subunit, which alters the conformation of the beta subunits
How does the PMF affect subunits? How does the PMF affect subunits? Answer: during rotation, gamma subunit rotates and interconverts beta subunits
The 3 catalytic subunits of the F1 component can exist in 3 conformations: The 3 catalytic subunits of the F1 component can exist in 3 conformations: 1: open (O) --> nucleotides bind to or release from beta 2: loose (L) --> nucleotides are trapped in beta 3: tight (T) --> ATP synthesized from ADP and Pi
What are the 2 components of ATP synthase? What are the 2 components of ATP synthase? Answer: F1: active sites, protrudes into matrix F0: embedded in inner-membrane, contains proton channel gamma subunit connects the 2
What reaction creates a proton gradient and What is this gradient important in powering? What reaction creates a proton gradient and What is this gradient important in powering? Answer: oxidation of NADH and FADH2 creates gradient and this powers the synthesis of ATP