2-Butanone is converted into 3-methyl-3-hexanol using a Grignard reagent prepared from 1-bromopropane and magnesium metal in THF solution. List the procedural steps required to collect the alcohol product by microdistillation.
Answer:
1) decant the dried THF solution into 25-mL round-bottom flask
2) add boiling chips to the solution in round-bottom flask
3) grease all joints and attach the flask to a micro distillation apparatus
4) set apparatus in heating mantle and use heat shield tiles
5) adjust Variac to distill THF at ~60ºC
6) Increase Variac setting to cause distillation of higher-boiling product
7) stop distillation before the flask becomes dry