Describe the flow of NADH's electrons.
Answer: NADH gives two electrons to FMN, the electrons then travel through a series of iron-sulfur clusters to get to Coenzyme Q. Coenzyme Q accepts the two electrons (and in the process also takes up 2 protons from the matrix to become QH2). All this flow of electrons from NADH to Coenzyme Q is coupled to the pumping of 4 protons out.
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Biochemistry
- How do liver and heart cells transport NADHs from glycolysis into the mit matrix and why do these still produce the full 2.5 ATPs?
- In the aldol cleavage of Fructose 1,6 bis phosphate to DHAP and GAP, why is there 96% DHAP?
- Why does the c ring rotate?
- Describe how ATP hydrolysis (the reverse reaction) can be visualized.
- Describe how the gamma and beta subunits of ATP synthase interact to allow ATP formation.
- Describe the structure of ATP synthase.
- Describe the experiment used to test the proton-motive force. Draw it.
- Describe the action on Complex IV.
- Describe how Complex III makes QH2 give up its protons.
- What is ubiquinone versus ubiquinol?
- Why does each NADH give 2.5 ATPs but each FADH2 only gives 1.5.
- What are the two special things about Complex II.
- Describe the structure of Complex I.
- What is the respirasome?