Describe how the gamma and beta subunits of ATP synthase interact to allow ATP formation.

Describe how the gamma and beta subunits of ATP synthase interact to allow ATP formation.



Answer: The gamma subunit as it rotates extends into the ring and breaks the symmetry of the hexamer by interacting with a beta subunit and changing the beta subunits conformation. The change in conformation causes the beta subunit to either be in a an open, tight or loose position. ATP is generated from ADP and Pi in the tight conformation and released in the loose conformation.


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