Describe how the gamma and beta subunits of ATP synthase interact to allow ATP formation.
Answer: The gamma subunit as it rotates extends into the ring and breaks the symmetry of the hexamer by interacting with a beta subunit and changing the beta subunits conformation. The change in conformation causes the beta subunit to either be in a an open, tight or loose position. ATP is generated from ADP and Pi in the tight conformation and released in the loose conformation.
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Biochemistry
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- Describe how ATP hydrolysis (the reverse reaction) can be visualized.
- Describe the structure of ATP synthase.
- Describe the experiment used to test the proton-motive force. Draw it.
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