Why does each NADH give 2.5 ATPs but each FADH2 only gives 1.5.
Answer: When FADH2 is taken up by Complex II, it undergoes the same transfer of electrons through iron-clusters and then to Coenzyme Q, and QH2 is formed however, this is all not coupled to a pumping of protons out at this point. (It is only involved in the Q protons while NADH is involved in the Q protons AND the pump at Complex I)
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Biochemistry
- How do liver and heart cells transport NADHs from glycolysis into the mit matrix and why do these still produce the full 2.5 ATPs?
- In the aldol cleavage of Fructose 1,6 bis phosphate to DHAP and GAP, why is there 96% DHAP?
- Why does the c ring rotate?
- Describe how ATP hydrolysis (the reverse reaction) can be visualized.
- Describe how the gamma and beta subunits of ATP synthase interact to allow ATP formation.
- Describe the structure of ATP synthase.
- Describe the experiment used to test the proton-motive force. Draw it.
- Describe the action on Complex IV.
- Describe how Complex III makes QH2 give up its protons.
- What is ubiquinone versus ubiquinol?
- What are the two special things about Complex II.
- Describe the flow of NADH's electrons.
- Describe the structure of Complex I.
- What is the respirasome?