What is true about the conversion of fructose 1,6-bisphosphate to fructose 6-phosphate? Gluconeogenesis What is true about the conversion of fructose 1,6-bisphosphate to fructose 6-phosphate? Answer: this is an irreversible step catalyzed by fructose 1,6-bisphosphatase Learn More : Share this Share on FacebookTweet on TwitterPlus on Google+